Biopatic Interventions
The most common treatments for cartilage deterioration are:
NSAIDs:NSAIDs reduce inflammation and reduce the risk of osteoarthritis. NSAIDs may increase pain and swelling and reduce the risk of rheumatoid arthritis.
Anti-inflammatory agents:Anti-inflammatory agents reduce inflammation, which may contribute to the joint damage and pain.
Osteoarthritis:NSAIDs reduce the risk of osteoarthritis. NSAIDs reduce pain and swelling.
Chronic joint pain:NSAIDs reduce inflammation. For osteoarthritis, NSAIDs reduce pain and inflammation.
Dosing:
The usual recommended dose of ibuprofen for adults with osteoarthritis of the knee and hip is 50 mg daily or 100 mg three times daily. The maximum recommended dose is 400 mg daily.
Administration:
Swallow the tablets whole with a full glass of water. You should start to feel the effects within a few hours. The tablets should be swallowed with a full glass of water. Do not crush or chew the tablets. Do not take more than one dose within a 24-hour period.
Contraindications:
NSAID– Patients should be aware of the following:
Allergic to the active ingredient;
Patients with a history of peptic ulcer disease, gastrointestinal bleeding or history of bleeding disorders;
Patients with severe kidney disease or liver disease;
Patients with known hypersensitivity to ibuprofen or to other active ingredients of the medicine;
Patients with liver disease;
Patients with severe cardiovascular disease or asthma;
Patients with known hypersensitivity to acetylsalicylic acid (ASA) or other nonsteroidal anti-inflammatory drugs (NSAIDs).
Other interactions
Dosing and effectiveness:
Dosing may not be affected by food or alcohol. For patients with a history of peptic ulcer, NSAIDs may be used with food and alcohol. It is recommended that ibuprofen is taken with a high-fat meal at the same time each day. In children and adolescents, it should be taken on an empty stomach. For children weighing more than 40 kg or adults weighing less than 40 kg, the usual dose is 400 to 600 mg three times a day. It is not recommended to take ibuprofen with a high-fat meal.
Safety and effectiveness:
Patients with severe kidney disease or liver disease should not take ibuprofen, unless their renal function is impaired. However, ibuprofen can be given with food or milk if the patient is overweight.
IBUPROFEN contains Ibuprofen which belongs to the group of medicines called Non-steroidal anti-inflammatory drugs (NSAIDs). It is used to relieve pain and inflammation in conditions such as osteoarthritis, rheumatoid arthritis (juvenile rheumatoid arthritis or Still's disease), arthritis of the spine, ankylosing spondylitis, swollen joints, frozen shoulder, bursitis, tendinitis, tenosynovitis, lower back pain, sprains and strains. This medicine can also be used to manage other painful conditions such as toothache, pain after operations, period pain, headache and migraine.
When your body is fighting an injury or infection, it naturally releases chemicals called prostaglandins which lead to fever, swelling and discomfort. IBUPROFEN blocks the effect of prostaglandins.
Before taking IBUPROFEN tell your doctor if you have liver, kidney or heart disease. Pregnant and breastfeeding women must consult the doctor before taking this medicine. Avoid excessive use of painkillers, tell your doctor if you are already taking another painkiller before taking this medicine. The common side effects are dizziness, tiredness, headache, diarrhea, constipation and flatulence.
ides by drug class beginsaxyx bral palsy groupIBUPROFEN contains Ibuprofen which belongs to the group of medicines called Non-steroidal Anti-Inflammatory drugs (NSAIDs).
The common side effects are dizziness, tiredness, headache, diarrhea, flatulence, constipation and tummy (spontaneity).
side effects of IBUPROFENTell your doctor if you have any of the following side effects:
diarrhoea, constipation, flatulence, tummy (spontaneity)Tell your doctor if you have any side effects not listed in this leaflet:- headache,
- stomach pain,
- constipation,
- indigestion,
- skin rash,
- tiredness,
- hot flushes,
- upset stomach,
- constipation during sex,
- dry mouth,
- dizziness,
- feeling sleepy or tired,
- sleep problems,
- changes in menstrual periods,
- breast pain,
- changes in the size of the uterus,
- changes in the shape of the uterus,
- changes in the mobility of the arms,
- changes in the menstrual period.
The above side effects are usually temporary and are not dangerous. Consult your doctor if you experience any serious side effects.
HOW SUPPLIEDStore below 25°C (77°F). Protect from light. Keep temperature controlled. Do not refrigerate. Protect from heat.
IBUPROFEN is safe for use in children and adolescents from 14 years of age. Ibuprofen is a weak inhibitor of cyclo-oxygenase (COX) enzymes. Therefore, it should only be used when a doctor has judged that the use could interact with any other medications.
IBUPROFEN is available in white, light yellow, and almost black tablets. The starting dose is one tablet every 4 to 6 hours as necessary. The tablets should be swallowed whole with a glass of water. The medicine should be taken with or without food.
Adults: Take 1 tablet every 4 to 6 hours as necessary. Swallow whole.
Ibuprofen is an ingredient in the medication. Ibuprofen (or a brand name of the ingredient) is the generic name for the painkiller. Ibuprofen is used to relieve mild to moderate pain, inflammation, or fever in children and adults. It can also be used to reduce fever. The medication is available as Advil or Motrin. Children under 16 years of age are not prescribed Advil for pain relief. Ibuprofen is only available with a child's prescription and is not used to treat fever. Ibuprofen should only be used under the guidance of a healthcare professional. Do not use Ibuprofen if you: are pregnant or breastfeeding. This medication should not be used during pregnancy or if you are breast feeding.
Read this leaflet carefully before you start taking ibuprofen and each time you get a refill. It is for you. There is a chance that you get a delayed response. You should get a new prescription first. Do not change the dose or stop taking the medication without talking to your healthcare professional.
The information on this page is not a substitute for professional medical advice, it is meant for educational purposes only. The information we provide depends on your specific condition and medical history. If you have any questions, consult with your doctor or pharmacist. Please remember that your doctor or pharmacist provides the information that you need. For medicines, services, products you buy from a pharmacy, supermarket or health food shop, telephone the Pharmacist or ask for the service. Otherwise, the information that you get from it may not be safe for everybody. Always ask your doctor or pharmacist if you are taking, not just any medicine. A medicine is not always the same as a hard copy of the strength on the page. The strength of your prescription is important. Your doctor or pharmacist can give you more information. You can check the strength of your prescription at the end of the leaflet. For a complete list of information, including what you should not take, see the “What is Ibuprofen” part of the product leaflet. You will have to ask your doctor or pharmacist for more information.
Tell your doctor if you are pregnant or breastfeeding, or if you have any allergies. Tell your doctor if you are taking any of the following medicines:
Do not use Ibuprofen if:
Your doctor has prescribed this medication for you. You may not be able to take Ibuprofen if you are pregnant or breastfeeding.
These medicines may be harmful to your unborn baby. Your doctor will be able to help you decide if this is the best course of treatment. If you are pregnant or breastfeeding, talk to your doctor before taking this medication. Your doctor may stop your baby if you are pregnant.
Tell your doctor if you have kidney or liver problems. These are common side effects of this medicine. Your doctor will be able to diagnose these problems with a simple, quick check of your urine output. If you are at risk of side effects, your doctor or pharmacist may also be able to tell you if you are taking other medicines that may interact with Ibuprofen, or with your other medicines.
Ibuprofen and other painkillers include:
These medicines may affect the action of Ibuprofen. If you have any doubts, talk to your doctor or pharmacist. Your doctor or pharmacist will be able to help you if you need to. The list of medicines that you take and any available treatment for them is limited. However, Ibuprofen can be used for a wide range of other conditions. See also Side Effects section. Ibuprofen is not usually recommended to be used for any other condition.
Ibuprofen is not usually recommended for use in children under 16 years of age.
If your child is at risk of developing serious side effects, such as liver or kidney problems, seek emergency help.
Tell your doctor or pharmacist if you are taking any other medicines, including any that you get while on ibuprofen.
Tell your doctor or pharmacist if you are taking any other medicines, including any that you get while taking ibuprofen.
Ibuprofen is used to relieve pain and inflammation in conditions such as osteoarthritis, rheumatoid arthritis (juvenile rheumatoid arthritis or Still's disease), arthritis of the spine, ankylosing spondylitis, swollen joints, frozen shoulder, bursitis, tendinitis, tenosynovitis, lower back pain, sprains and strains.
It can also be used to treat other painful conditions such as toothache, pain after operations, period pain, headache and migraine.
Ibuprofen: Non-steroidal anti-inflammatory drugs (NSAIDs)
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Not for use in children or if you are allergic to Ibuprofen, aspirin or other anti-inflammatory drugs, or any of the other ingredients of this medicine.
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